Pharmacological Interventions: Prokinetics and Antiemetics

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2025-12-22 10:22:51 -

The primary goal of pharmacological treatment in gastroparesis is to enhance gastric motility (prokinetics) and control symptoms (antiemetics). Metoclopramide remains the only FDA-approved medication specifically for gastroparesis. It acts as a dopamine D2 receptor antagonist and a 5-HT4 receptor agonist, promoting antral contractions. However, its use is limited by a "Black Box Warning"...

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